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Target
Cholecystokinin receptor type A
Ligand
BDBM50063660
Substrate
n/a
Meas. Tech.
ChEBML_50206
IC50
>1000±n/a nM
Citation
 Padia, JK; Chilvers, H; Daum, P; Pinnock, R; Suman-Chauhan, N; webdale, L; Trivedi, BK Design and synthesis of novel nonpeptide CCK-B receptor antagonists Bioorg Med Chem Lett 7:805-810 (1997)    Article 
Target
Name:
Cholecystokinin receptor type A
Synonyms:
CCKAR_RAT | Cckar | Cholecystokinin peripheral | Cholecystokinin receptor | Cholecystokinin receptor type A
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49676.37
Organism:
RAT
Description:
Cholecystokinin central 0 RAT::P30551
Residue:
444
Sequence:
MSHSPARQHLVESSRMDVVDSLLMNGSNITPPCELGLENETLFCLDQPQPSKEWQSALQILLYSIIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLLPGIVMVVAYGLISLELYQGIKFDASQKKSAKEKKPSTGSSTRYEDSDGCYLQKSRPPRKLELQQLSSGSGGSRLNRIRSSSSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCPNPGPPGVRGEVGEEEDGRTIRALLSRYSYSHMSTSAPPP
  
Inhibitor
Name:
BDBM50063660
Synonyms:
1-(4-Bromo-phenyl)-3-[3-(3-isopropoxy-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-yl]-urea | CHEMBL264087
Type:
Small organic molecule
Emp. Form.:
C24H21BrN4O3
Mol. Mass.:
493.353
SMILES:
CC(C)Oc1cccc(c1)-n1c(NC(=O)Nc2ccc(Br)cc2)nc2ccccc2c1=O
Structure:
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