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Target
Metalloproteinase inhibitor 3
Ligand
BDBM50291444
Substrate
n/a
Meas. Tech.
ChEMBL_104907 (CHEMBL713443)
IC50
810±n/a nM
Citation
 Baxter, AD; Bird, J; Bhogal, R; Massil, T; Minton, KJ; Montana, J; Owen, DA A novel series of matrix metalloproteinase inhibitors for the treatment of inflammatory disorders Bioorg Med Chem Lett 7:897-902 (1997)    Article 
Target
Name:
Metalloproteinase inhibitor 3
Synonyms:
TIMP3_RAT | Timp-3 | Timp3 | Tissue inhibitor of metalloproteinases 3 | Tissue inhibitor of metalloproteinases-3
Type:
PROTEIN
Mol. Mass.:
24241.51
Organism:
Rattus norvegicus
Description:
ChEMBL_10750
Residue:
211
Sequence:
MTPWLGLVVLLSCWSLGHWGTEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFSKMPHVQYIHTEASESLCGLKLEVNKYQYLLTGRVYEGKMYTGLCNFVERWDHLTLSQRKGLNYRYHLGCNCKIKSCYYLPCFVTSKKECLWTDMLSNFGYPGYQSKHYACIRQKGGYCSWYRGWAPPDKSISNATDP
  
Inhibitor
Name:
BDBM50291444
Synonyms:
(R)-N-[(S)-2-(1H-Indol-3-yl)-1-methylcarbamoyl-ethyl]-2-(2-mercapto-acetylamino)-3-methylsulfanyl-propionamide | CHEMBL369024
Type:
Small organic molecule
Emp. Form.:
C18H24N4O3S2
Mol. Mass.:
408.538
SMILES:
CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CSC)NC(=O)CS
Structure:
Search PDB for entries with ligand similarity: