Reaction Details Report a problem with these data
Target
C5a anaphylatoxin chemotactic receptor 1
Ligand
BDBM50291468
Substrate
n/a
Meas. Tech.
ChEBML_41460
IC50
4000±n/a nM
Citation
 Astles, PC; Brown, TJ; Cox, P; Halley, F; Lockey, PM; McCarthy, C; McLay, IM; Majid, TN; Morley, AD; Porter, B; Ratcliffe, AJ; Walsh, RJ New non peptidic C5a receptor antagonists Bioorg Med Chem Lett 7:907-912 (1997)    Article 
Target
Name:
C5a anaphylatoxin chemotactic receptor 1
Synonyms:
C5AR | C5AR1 | C5AR1_HUMAN | C5R1 | C5a anaphylatoxin chemotactic receptor | C5a anaphylatoxin chemotactic receptor (C5aR) | C5a-R | CD_antigen=CD88
Type:
Enzyme
Mol. Mass.:
39347.68
Organism:
Homo sapiens (Human)
Description:
P21730
Residue:
350
Sequence:
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
  
Inhibitor
Name:
BDBM50291468
Synonyms:
CHEMBL170859 | N-(4-Benzyloxy-3-phenoxy-phenyl)-N'-methyl-guanidine
Type:
Small organic molecule
Emp. Form.:
C21H21N3O2
Mol. Mass.:
347.4103
SMILES:
CNC(N)=Nc1ccc(OCc2ccccc2)c(Oc2ccccc2)c1 |w:4.4|
Structure:
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