Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50294505
Substrate
n/a
Meas. Tech.
ChEMBL_575574 (CHEMBL1036417)
Ki
137±n/a nM
Citation
 Gillespie, RJ; Bamford, SJ; Gaur, S; Jordan, AM; Lerpiniere, J; Mansell, HL; Stratton, GC Antagonists of the human A(2A) receptor. Part 5: Highly bio-available pyrimidine-4-carboxamides. Bioorg Med Chem Lett 19:2664-7 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50294505
Synonyms:
2-amino-N-(2-chlorobenzyl)-6-(furan-2-yl)pyrimidine-4-carboxamide | CHEMBL560904
Type:
Small organic molecule
Emp. Form.:
C16H13ClN4O2
Mol. Mass.:
328.753
SMILES:
Nc1nc(cc(n1)-c1ccco1)C(=O)NCc1ccccc1Cl
Structure:
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