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Target
Tyrosinase
Ligand
BDBM50296245
Substrate
n/a
Meas. Tech.
ChEMBL_579688 (CHEMBL1053202)
Ki
64000±n/a nM
Citation
 Yamazaki, Y; Kawano, Y; Yamanaka, A; Maruyama, S N-[(Dihydroxyphenyl)acyl]serotonins as potent inhibitors of tyrosinase from mouse and human melanoma cells. Bioorg Med Chem Lett 19:4178-82 (2009) [PubMed]  Article 
Target
Name:
Tyrosinase
Synonyms:
TYRO_MOUSE | Tyr
Type:
Protein
Mol. Mass.:
60600.74
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
533
Sequence:
MFLAVLYCLLWSFQISDGHFPRACASSKNLLAKECCPPWMGDGSPCGQLSGRGSCQDILLSSAPSGPQFPFKGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFGGPNCTEKRVLIRRNIFDLSVSEKNKFFSYLTLAKHTISSVYVIPTGTYGQMNNGSTPMFNDINIYDLFVWMHYYVSRDTLLGGSEIWRDIDFAHEAPGFLPWHRLFLLLWEQEIRELTGDENFTVPYWDWRDAENCDICTDEYLGGRHPENPNLLSPASFFSSWQIICSRSEEYNSHQVLCDGTPEGPLLRNPGNHDKAKTPRLPSSADVEFCLSLTQYESGSMDRTANFSFRNTLEGFASPLTGIADPSQSSMHNALHIFMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLLEVYPEANAPIGHNRDSYMVPFIPLYRNGDFFITSKDLGYDYSYLQESDPGFYRNYIEPYLEQASRIWPWLLGAALVGAVIAAALSGLSSRLCLQKKKKKKQPQEERQPLLMDKDDYHSLLYQSHL
  
Inhibitor
Name:
BDBM50296245
Synonyms:
3,4-Dihydroxy-N-[2-(5-hydroxyindol-3-yl)ethyl]benzamide | CHEMBL552171
Type:
Small organic molecule
Emp. Form.:
C17H16N2O4
Mol. Mass.:
312.3199
SMILES:
Oc1ccc2[nH]cc(CCNC(=O)c3ccc(O)c(O)c3)c2c1
Structure:
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