Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50304636
Substrate
n/a
Meas. Tech.
ChEMBL_604437 (CHEMBL1070693)
Ki
1.19±n/a nM
Citation
 Choi, WJ; Lee, HW; Kim, HO; Chinn, M; Gao, ZG; Patel, A; Jacobson, KA; Moon, HR; Jung, YH; Jeong, LS Design and synthesis of N(6)-substituted-4'-thioadenosine-5'-uronamides as potent and selective human A(3) adenosine receptor agonists. Bioorg Med Chem 17:8003-11 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50304636
Synonyms:
CHEMBL608680 | N6-Methyl-9-(5'-methylaminocarbonyl-4'-thio-beta-D-ribofuranosyl)adenine
Type:
Small organic molecule
Emp. Form.:
C12H16N6O3S
Mol. Mass.:
324.359
SMILES:
CNC(=O)[C@H]1S[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NC)ncnc12 |r|
Structure:
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