Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50308568
Substrate
n/a
Meas. Tech.
ChEMBL_613655 (CHEMBL1066998)
Ki
23.2±n/a nM
Citation
 Hierrezuelo, J; Manuel López-Romero, J; Rico, R; Brea, J; Isabel Loza, M; Cai, C; Algarra, M Synthesis of theophylline derivatives and study of their activity as antagonists at adenosine receptors. Bioorg Med Chem 18:2081-8 (2010) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Homo sapiens (Human)
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50308568
Synonyms:
2-(2-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy)acetamide | CHEMBL589288
Type:
Small organic molecule
Emp. Form.:
C19H23N5O4
Mol. Mass.:
385.417
SMILES:
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1ccccc1OCC(N)=O
Structure:
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