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Target
Mu-type opioid receptor
Ligand
BDBM50310298
Substrate
n/a
Meas. Tech.
ChEMBL_607972 (CHEMBL1071742)
IC50
>1000±n/a nM
Citation
 Imaide, S; Fujii, H; Watanabe, A; Nemoto, T; Nakajima, M; Nakao, K; Mochizuki, H; Nagase, H Investigation of Beckett-Casy model 1: synthesis of novel 16,17-seco-naltrexone derivatives and their pharmacology. Bioorg Med Chem Lett 20:1055-8 (2010) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50310298
Synonyms:
(2aS,2a1S,5aR)-2a1-(2-(1H-1,2,3-triazol-1-yl)ethyl)-2-((cyclopropylmethyl)(methyl)amino)-2a,7-dihydroxy-2,2a,2a1,3,4,5a-hexahydrophenanthro[4,5-bcd]furan-5(1H)-one hydrochloride | CHEMBL599533
Type:
Small organic molecule
Emp. Form.:
C23H28N4O4
Mol. Mass.:
424.4928
SMILES:
CN(CC1CC1)C1Cc2ccc(O)c3O[C@H]4C(=O)CC[C@]1(O)[C@@]4(CCn1ccnn1)c23 |r|
Structure:
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