Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM50313816
Substrate
n/a
Meas. Tech.
ChEMBL_615225 (CHEMBL1115875)
Ki
>4200±n/a nM
Citation
 Brown, A; Ellis, D; Wallace, O; Ralph, M Identification of a urea bioisostere of a triazole oxytocin antagonist. Bioorg Med Chem Lett 20:1851-3 (2010) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM50313816
Synonyms:
5-(3-(3-(3,5-difluoro-2-methylphenoxy)azetidin-1-yl)-5-methyl-4H-1,2,4-triazol-4-yl)-2-methoxypyridine | CHEMBL1091817
Type:
Small organic molecule
Emp. Form.:
C19H19F2N5O2
Mol. Mass.:
387.3833
SMILES:
COc1ccc(cn1)-n1c(C)nnc1N1CC(C1)Oc1cc(F)cc(F)c1C
Structure:
Search PDB for entries with ligand similarity: