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Target
Macrophage migration inhibitory factor
Ligand
BDBM50313986
Substrate
n/a
Meas. Tech.
ChEMBL_615752 (CHEMBL1100106)
IC50
38±n/a nM
Citation
 McLean, LR; Zhang, Y; Li, H; Choi, YM; Han, Z; Vaz, RJ; Li, Y Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site. Bioorg Med Chem Lett 20:1821-4 (2010) [PubMed]  Article 
Target
Name:
Macrophage migration inhibitory factor
Synonyms:
GIF | GLIF | Glycosylation-inhibiting factor | L-dopachrome isomerase | L-dopachrome tautomerase | MIF | MIF/CD74 (Macrophage migration inhibitory factor and HLA-DR antigens-associated invariant chain) | MIF_HUMAN | MMIF | Macrophage migration inhibitory factor | Macrophage migration inhibitory factor (MIF) | Phenylpyruvate tautomerase
Type:
Enzyme
Mol. Mass.:
12478.18
Organism:
Homo sapiens (Human)
Description:
P14174
Residue:
115
Sequence:
MPMFIVNTNVPRASVPDGFLSELTQQLAQATGKPPQYIAVHVVPDQLMAFGGSSEPCALCSLHSIGKIGGAQNRSYSKLLCGLLAERLRISPDRVYINYYDMNAANVGWNNSTFA
  
Inhibitor
Name:
BDBM50313986
Synonyms:
3-(3,4-dihydroxyphenyl)-4H-chromen-4-one | CHEMBL1089054
Type:
Small organic molecule
Emp. Form.:
C15H10O4
Mol. Mass.:
254.2375
SMILES:
Oc1ccc(cc1O)-c1coc2ccccc2c1=O
Structure:
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