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Target
Arginase-1
Ligand
BDBM50316608
Substrate
n/a
Meas. Tech.
ChEMBL_631783 (CHEMBL1108176)
Ki
3600000±n/a nM
Citation
 Ilies, M; Di Costanzo, L; North, ML; Scott, JA; Christianson, DW 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. J Med Chem 53:4266-76 (2010) [PubMed]  Article 
Target
Name:
Arginase-1
Synonyms:
ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase
Type:
PROTEIN
Mol. Mass.:
34737.53
Organism:
Homo sapiens (Human)
Description:
ChEMBL_978893
Residue:
322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPNDSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAITLACFGLAREGNHKPIDYLNPPK
  
Inhibitor
Name:
BDBM50316608
Synonyms:
1H-Imidazol-2-yl-ammonium | 1H-Imidazol-2-ylamine | 1H-imidazol-2-amine | 2-Aminoimidazole | CHEMBL2392115 | CHEMBL291627
Type:
Small organic molecule
Emp. Form.:
C3H5N3
Mol. Mass.:
83.0919
SMILES:
Nc1ncc[nH]1
Structure:
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