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Target
Virokine/NFkB inhibitor
Ligand
BDBM50316623
Substrate
n/a
Meas. Tech.
ChEMBL_631987 (CHEMBL1107435)
IC50
2400±n/a nM
Citation
 Cheltsov, AV; Aoyagi, M; Aleshin, A; Yu, EC; Gilliland, T; Zhai, D; Bobkov, AA; Reed, JC; Liddington, RC; Abagyan, R Vaccinia virus virulence factor N1L is a novel promising target for antiviral therapeutic intervention. J Med Chem 53:3899-906 (2010) [PubMed]  Article 
Target
Name:
Virokine/NFkB inhibitor
Synonyms:
N1L
Type:
PROTEIN
Mol. Mass.:
13954.85
Organism:
Vaccinia virus
Description:
ChEMBL_631987
Residue:
117
Sequence:
MRTLLIRYILWRNDNDQTYYNDDFKKLMLLDELVDDGDVCTLIKNMRMTLSDGPLLDRLNQPVNNIEDAKRMIAISAKVARDIGERSEIRWEESFTILFRMIETYFDDLMIDLYGEK
  
Inhibitor
Name:
BDBM50316623
Synonyms:
(N,N)-N,N'-(1,2-bis(3,4,5-trimethoxyphenyl)ethane-1,2-diylidene)dianiline | CHEMBL1098118
Type:
Small organic molecule
Emp. Form.:
C32H32N2O6
Mol. Mass.:
540.6063
SMILES:
COc1cc(cc(OC)c1OC)\C(=N/c1ccccc1)\C(=N\c1ccccc1)\c1cc(OC)c(OC)c(OC)c1
Structure:
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