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Target
Thymidine kinase
Ligand
BDBM50317618
Substrate
n/a
Meas. Tech.
ChEMBL_632671 (CHEMBL1112809)
IC50
120000±n/a nM
Citation
 Lin, J; Roy, V; Wang, L; You, L; Agrofoglio, LA; Deville-Bonne, D; McBrayer, TR; Coats, SJ; Schinazi, RF; Eriksson, S 3'-(1,2,3-Triazol-1-yl)-3'-deoxythymidine analogs as substrates for human and Ureaplasma parvum thymidine kinase for structure-activity investigations. Bioorg Med Chem 18:3261-9 (2010) [PubMed]  Article 
Target
Name:
Thymidine kinase
Synonyms:
KITH_UREPA | tdk
Type:
PROTEIN
Mol. Mass.:
25374.94
Organism:
Ureaplasma parvum
Description:
ChEMBL_632671
Residue:
223
Sequence:
MAKVNAFSKKIGWIELITGPMFAGKTAELIRRLHRLEYADVKYLVFKPKIDTRSIRNIQSRTGTSLPSVEVESAPEILNYIMSNSFNDETKVIGIDEVQFFDDRICEVANILAENGFVVIISGLDKNFKGEPFGPIAKLFTYADKITKLTAICNECGAEATHSLRKIDGKHADYNDDIVKIGCQEFYSAVCRHHHKVPNRPYLNSNSEEFIKFFKNKKRNKNI
  
Inhibitor
Name:
BDBM50317618
Synonyms:
3'-(4-(2-Phenyl-ethyl)-1,2,3-triazole-1-yl)-2'-deoxythymidine | CHEMBL1096828
Type:
Small organic molecule
Emp. Form.:
C20H23N5O4
Mol. Mass.:
397.4277
SMILES:
Cc1cn([C@H]2C[C@@H]([C@@H](CO)O2)n2cc(CCc3ccccc3)nn2)c(=O)[nH]c1=O |r|
Structure:
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