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Target
Alpha-galactosidase
Ligand
BDBM50320826
Substrate
n/a
Meas. Tech.
ChEMBL_639187 (CHEMBL1168040)
pH
6.5±n/a
IC50
1200±n/a nM
Comments
extracted
Citation
 Kato, A; Yamashita, Y; Nakagawa, S; Koike, Y; Adachi, I; Hollinshead, J; Nash, RJ; Ikeda, K; Asano, N 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem 18:3790-4 (2010) [PubMed]  Article 
Target
Name:
Alpha-galactosidase
Synonyms:
α-galactosidase | AGAL_COFAR | Alpha-galactosidase
Type:
Protein
Mol. Mass.:
41306.82
Organism:
Coffea arabica (Coffee beans)
Description:
n/a
Residue:
378
Sequence:
MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGYKYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTMPGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWGEEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGMTTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYGDLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQISAAVDAHDSKMYVLTPQ
  
Inhibitor
Name:
BDBM50320826
Synonyms:
CHEMBL1163255 | beta-1-C-Butyl-1-deoxygalactonojirimycin
Type:
Small organic molecule
Emp. Form.:
C11H23NO3
Mol. Mass.:
217.3052
SMILES:
CCCC[C@@H]1N[C@H](CO)[C@H](O)[C@H](O)[C@H]1C |r|
Structure:
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