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Target
Alpha-galactosidase
Ligand
BDBM50320827
Substrate
n/a
Meas. Tech.
ChEMBL_639187 (CHEMBL1168040)
pH
6.5000±n/a
IC50
2000±n/a nM
Comments
extracted
Citation
 Kato, A; Yamashita, Y; Nakagawa, S; Koike, Y; Adachi, I; Hollinshead, J; Nash, RJ; Ikeda, K; Asano, N 2,5-Dideoxy-2,5-imino-d-altritol as a new class of pharmacological chaperone for Fabry disease. Bioorg Med Chem 18:3790-4 (2010) [PubMed]  Article 
Target
Name:
Alpha-galactosidase
Synonyms:
AGAL_COFAR | α-galactosidase | Alpha-galactosidase
Type:
Protein
Mol. Mass.:
41306.82
Organism:
Arabian coffee
Description:
n/a
Residue:
378
Sequence:
MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGYKYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTMPGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWGEEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGMTTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYGDLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQISAAVDAHDSKMYVLTPQ
  
Inhibitor
Name:
BDBM50320827
Synonyms:
beta-1-C-butenyl-1-deoxygalactonojirimycin | CHEMBL1163562
Type:
Small organic molecule
Emp. Form.:
C11 H21 N O3
Mol. Mass.:
215.28934
SMILES:
C[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)N[C@H]1CCC=C |r|
Structure:
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