Target
Carbonic anhydrase 3
Ligand
BDBM50323739
Substrate
n/a
Meas. Tech.
ChEMBL_646955 (CHEMBL1217096)
Ki
520±n/a nM
Citation
 Carta, FTemperini, CInnocenti, AScozzafava, AKaila, KSupuran, CT Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. J Med Chem 53:5511-22 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 3
Synonyms:
CA-III | CA3 | CAH3_HUMAN | Carbonate dehydratase III | Carbonic Anhydrase III | Carbonic anhydrase | Carbonic anhydrase 3 (CA III) | Carbonic anhydrase III (CA III)
Type:
Enzyme
Mol. Mass.:
29562.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
260
Sequence:
MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK
  
Inhibitor
Name:
BDBM50323739
Synonyms:
CHEMBL1214194 | N1,N1'-(ethane-1,2-diyl)bis(N1,N2,N2-trimethylethane-1,2-diamine)
Type:
Small organic molecule
Emp. Form.:
C12H30N4
Mol. Mass.:
230.3934
SMILES:
CN(C)CCN(C)CCN(C)CCN(C)C
Structure:
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