Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50323756
Substrate
n/a
Meas. Tech.
ChEMBL_646968 (CHEMBL1217109)
Ki
15000±n/a nM
Citation
 Dixon, DD; Sethumadhavan, D; Benneche, T; Banaag, AR; Tius, MA; Thakur, GA; Bowman, A; Wood, JT; Makriyannis, A Heteroadamantyl cannabinoids. J Med Chem 53:5656-66 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50323756
Synonyms:
(6aR,9R,10aR)-6,6-Dimethyl-3-(2-oxa-6-aza-tricyclo[3.3.1.1*3,7*]dec-6-ylmethyl)-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromene-1,9-diol | CHEMBL1214434
Type:
Small organic molecule
Emp. Form.:
C24H33NO4
Mol. Mass.:
399.5231
SMILES:
CC1(C)Oc2cc(CN3C4CC5CC3CC(C4)O5)cc(O)c2[C@@H]2C[C@H](O)CC[C@@H]12 |r,TLB:7:8:11.10.12:15.14.16,12:11:8.13.14:16,THB:7:8:11.17.10:16,17:15:8:11.10.12,17:11:8:15.14.16,12:13:11.17.10:16|
Structure:
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