Reaction Details Report a problem with these data
Target
Lactoylglutathione lyase
Ligand
BDBM50326997
Substrate
n/a
Meas. Tech.
ChEMBL_663474 (CHEMBL1251073)
IC50
1900±n/a nM
Citation
 Takasawa, R; Saeki, K; Tao, A; Yoshimori, A; Uchiro, H; Fujiwara, M; Tanuma, S Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I. Bioorg Med Chem 18:7029-33 (2010) [PubMed]  Article 
Target
Name:
Lactoylglutathione lyase
Synonyms:
Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase
Type:
Enzyme
Mol. Mass.:
20772.95
Organism:
Homo sapiens (Human)
Description:
Q04760
Residue:
184
Sequence:
MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQKCDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNSDPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKMATLM
  
Inhibitor
Name:
BDBM50326997
Synonyms:
CHEMBL590878 | Delphinidin
Type:
Small organic molecule
Emp. Form.:
C15H11O7
Mol. Mass.:
303.2431
SMILES:
Oc1cc2oc(c(O)cc2c(=[OH+])c1)-c1cc(O)c(O)c(O)c1
Structure:
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