Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50328662
Substrate
n/a
Meas. Tech.
ChEMBL_665780 (CHEMBL1259271)
Ki
32.6±n/a nM
Citation
 Nikas, SP; Alapafuja, SO; Papanastasiou, I; Paronis, CA; Shukla, VG; Papahatjis, DP; Bowman, AL; Halikhedkar, A; Han, X; Makriyannis, A Novel 1',1'-chain substituted hexahydrocannabinols: 9ß-hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a highly potent cannabinoid receptor 1 (CB1) agonist. J Med Chem 53:6996-7010 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50328662
Synonyms:
(6aR,10aR)-3-(2-Hexyl-1,3-dithiolan-2-yl)-6,6a,7,8,10,10ahexahydro-1-hydroxy-6,6-dimethyl-9H-dibenzo[b,d]pyran-9-one | CHEMBL1259000
Type:
Small organic molecule
Emp. Form.:
C24H34O3S2
Mol. Mass.:
434.655
SMILES:
CCCCCCC1(SCCS1)c1cc(O)c2[C@@H]3CC(=O)CC[C@H]3C(C)(C)Oc2c1 |r|
Structure:
Search PDB for entries with ligand similarity: