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Target
NS5B
Ligand
BDBM50183494
Substrate
n/a
Meas. Tech.
ChEMBL_673141 (CHEMBL1268646)
IC50
302±n/a nM
Citation
 Powdrill, MH; Deval, J; Narjes, F; De Francesco, R; Götte, M Mechanism of hepatitis C virus RNA polymerase inhibition with dihydroxypyrimidines. Antimicrob Agents Chemother 54:977-83 (2010) [PubMed]  Article 
Target
Name:
NS5B
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
16859.41
Organism:
Hepatitis C virus
Description:
ChEMBL_695368
Residue:
152
Sequence:
MLVCGDDLVVIAESDGVEEDKRALGAFTEAMTRYSAPPGDAPQPAYDLELITSCSSNVSVAHDETGKRVYYLTRDPETPLARAAWETARHTPVNSWLGNIIIYAPTIWVRMVLMTHFFSILQSQEALEKALDFDMYGVTYSITPLDLPAIIQ
  
Inhibitor
Name:
BDBM50183494
Synonyms:
2-[3-({[(2,6-dichlorobenzyl)oxy]carbonyl}amino)-2-thienyl]-5,6-dihydroxy-pyrimidine-4-carboxylic acid | CHEMBL205990
Type:
Small organic molecule
Emp. Form.:
C17H11Cl2N3O6S
Mol. Mass.:
456.257
SMILES:
OC(=O)c1nc([nH]c(=O)c1O)-c1sccc1NC(=O)OCc1c(Cl)cccc1Cl
Structure:
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