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Target
Carbonic anhydrase 13
Ligand
BDBM50329822
Substrate
n/a
Meas. Tech.
ChEMBL_675715 (CHEMBL1272349)
Kd
1000±n/a nM
Citation
 Capkauskaite, E; Baranauskiene, L; Golovenko, D; Manakova, E; Gražulis, S; Tumkevičius, S; Matulis, D Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII. Bioorg Med Chem 18:7357-64 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII)
Type:
Enzyme
Mol. Mass.:
29445.78
Organism:
Homo sapiens (Human)
Description:
Q8N1Q1
Residue:
262
Sequence:
MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH
  
Inhibitor
Name:
BDBM50329822
Synonyms:
5-[(2-Benzyl-1H-benzimidazol-1-yl)acetyl]-2-chlorobenzenesulfonamide | CHEMBL1272242 | N-alkylated benzimidazole derivative, 4d | carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 5
Type:
Small organic molecule
Emp. Form.:
C22H18ClN3O3S
Mol. Mass.:
439.915
SMILES:
NS(=O)(=O)c1cc(ccc1Cl)C(=O)Cn1c(Cc2ccccc2)nc2ccccc12
Structure:
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