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Target
Chymotrypsinogen A
Ligand
BDBM50330784
Substrate
n/a
Meas. Tech.
ChEMBL_685422 (CHEMBL1285321)
IC50
>500000±n/a nM
Citation
 Eidam, O; Romagnoli, C; Caselli, E; Babaoglu, K; Pohlhaus, DT; Karpiak, J; Bonnet, R; Shoichet, BK; Prati, F Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids asß-lactamase inhibitors. J Med Chem 53:7852-63 (2010) [PubMed]  Article 
Target
Name:
Chymotrypsinogen A
Synonyms:
Alpha-chymotrypsin | CTRA_BOVIN | Chymotrypsin A | Chymotrypsin A chain A | Chymotrypsin A chain B | Chymotrypsin A chain C | Chymotrypsinogen A | alpha-Chymotrypsin (α-Chymotrypsin)
Type:
Serine protease
Mol. Mass.:
25670.88
Organism:
Bos taurus (bovine)
Description:
n/a
Residue:
245
Sequence:
CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTSTPGVYARVTALVNWVQQTLAAN
  
Inhibitor
Name:
BDBM50330784
Synonyms:
CHEMBL1231476 | Pinacol(Phenylmethanesulfonylamino)methaneboronate | {[(benzylsulfonyl)amino]methyl}boronic acid
Type:
Small organic molecule
Emp. Form.:
C8H12BNO4S
Mol. Mass.:
229.061
SMILES:
OB(O)CNS(=O)(=O)Cc1ccccc1
Structure:
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