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Target
Cannabinoid receptor 1
Ligand
BDBM50332244
Substrate
n/a
Meas. Tech.
ChEMBL_685959 (CHEMBL1292715)
Ki
>10000±n/a nM
Citation
 Osman, NA; Mahmoud, AH; Allarà, M; Niess, R; Abouzid, KA; Di Marzo, V; Abadi, AH Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. Bioorg Med Chem 18:8463-77 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50332244
Synonyms:
(E)-6-(3,4-Dimethoxyphenyl)4-oxohex-5-enoic acid piperedinamide | CHEMBL1288088
Type:
Small organic molecule
Emp. Form.:
C19H25NO4
Mol. Mass.:
331.4061
SMILES:
COc1ccc(C=CC(=O)CCC(=O)N2CCCCC2)cc1OC |w:6.5|
Structure:
Search PDB for entries with ligand similarity: