Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50332258
Substrate
n/a
Meas. Tech.
ChEMBL_685959 (CHEMBL1292715)
Ki
>10000±n/a nM
Citation
 Osman, NA; Mahmoud, AH; Allarà, M; Niess, R; Abouzid, KA; Di Marzo, V; Abadi, AH Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. Bioorg Med Chem 18:8463-77 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50332258
Synonyms:
(E)-7-Naphthalen-2-yl-5-oxohept-6-enoic acid(2-hydroxy-1(R)-methylethanolamide | CHEMBL1288237
Type:
Small organic molecule
Emp. Form.:
C20H23NO3
Mol. Mass.:
325.4015
SMILES:
C[C@@H](CO)NC(=O)CCCC(=O)C=Cc1ccc2ccccc2c1 |r,w:13.13|
Structure:
Search PDB for entries with ligand similarity: