Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50332256
Substrate
n/a
Meas. Tech.
ChEMBL_685961 (CHEMBL1292717)
IC50
8020±n/a nM
Citation
 Osman, NA; Mahmoud, AH; Allarà, M; Niess, R; Abouzid, KA; Di Marzo, V; Abadi, AH Synthesis, binding studies and molecular modeling of novel cannabinoid receptor ligands. Bioorg Med Chem 18:8463-77 (2010) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50332256
Synonyms:
(E)-7-Naphthalen-2-yl-5-oxohept-6-enoic acid cyclopropylamide | CHEMBL1288209
Type:
Small organic molecule
Emp. Form.:
C20H21NO2
Mol. Mass.:
307.3862
SMILES:
O=C(CCCC(=O)C=Cc1ccc2ccccc2c1)NC1CC1 |w:8.8|
Structure:
Search PDB for entries with ligand similarity: