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Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM50332458
Substrate
n/a
Meas. Tech.
ChEMBL_696726 (CHEMBL1638638)
IC50
973±n/a nM
Citation
 Choi, J; Park, Y; Lee, HS; Yang, Y; Yoon, S 1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPAR¿ partial agonists. Bioorg Med Chem 18:8315-23 (2010) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM50332458
Synonyms:
4-nitrophenyl 1,3-diphenyl-1H-pyrazole-4-carboxylate | CHEMBL1629930
Type:
Small organic molecule
Emp. Form.:
C22H15N3O4
Mol. Mass.:
385.3722
SMILES:
[O-][N+](=O)c1ccc(OC(=O)c2cn(nc2-c2ccccc2)-c2ccccc2)cc1
Structure:
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