Reaction Details Report a problem with these data
Target
Peroxisome proliferator-activated receptor delta
Ligand
BDBM50332462
Substrate
n/a
Meas. Tech.
ChEMBL_696426 (CHEMBL1640279)
EC50
0.9±n/a nM
Citation
 Chin, J; Hong, JY; Lee, J; Hwang, H; Ko, H; Choi, H; Hahn, D; Ko, J; Nam, SJ; Tak, J; Ham, J; Kang, H Selective peroxisome proliferator-activated receptord isosteric selenium agonists as potent anti-atherogenic agents in vivo. Bioorg Med Chem Lett 20:7239-42 (2010) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor delta
Synonyms:
NR1C2 | NUC1 | NUCI | Nuclear hormone receptor 1 | Nuclear receptor subfamily 1 group C member 2 | PPAR delta | PPAR-beta | PPARB | PPARD | PPARD_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor beta | Peroxisome proliferator-activated receptor delta
Type:
Enzyme
Mol. Mass.:
49910.45
Organism:
Homo sapiens (Human)
Description:
Q03181
Residue:
441
Sequence:
MEQPQEEAPEVREEEEKEEVAEAEGAPELNGGPQHALPSSSYTDLSRSSSPPSLLDQLQMGCDGASCGSLNMECRVCGDKASGFHYGVHACEGCKGFFRRTIRMKLEYEKCERSCKIQKKNRNKCQYCRFQKCLALGMSHNAIRFGRMPEAEKRKLVAGLTANEGSQYNPQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKASHTAPFVIHDIETLWQAEKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEIYKDMY
  
Inhibitor
Name:
BDBM50332462
Synonyms:
2-(2-methyl-4-((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methylselanyl)phenoxy)acetic acid | 2-methyl-4-((4-methyl-2-(4-trifluoromethylphenyl)-1,3-selenazol-5-yl)-methylsulfanyl)phenoxy-acetic acid | CHEMBL1169827
Type:
Small organic molecule
Emp. Form.:
C21H18F3NO3SSe
Mol. Mass.:
500.39
SMILES:
Cc1nc(sc1C[Se]c1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: