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Target
Inositol phosphorylceramide synthase
Ligand
BDBM50333120
Substrate
n/a
Meas. Tech.
ChEMBL_690931 (CHEMBL1634539)
Ki
16±n/a nM
Citation
 Aeed, PA; Young, CL; Nagiec, MM; Elhammer, AP Inhibition of inositol phosphorylceramide synthase by the cyclic peptide aureobasidin A. Antimicrob Agents Chemother 53:496-504 (2009) [PubMed]  Article 
Target
Name:
Inositol phosphorylceramide synthase
Synonyms:
AUR1 | AUR1_CANAL | Aureobasidin A resistance protein homolog | IPC synthase | Phosphatidylinositol:ceramide phosphoinositol transferase
Type:
PROTEIN
Mol. Mass.:
53452.25
Organism:
Candida albicans
Description:
ChEMBL_690931
Residue:
471
Sequence:
MASSILRSKIIQKPYQLFHYYFLSEKAPGSTVSDLNFDTNIQTSLRKLKHHHWTVGEIFHYGFLVSILFFVFVVFPASFFIKLPIILAFATCFLIPLTSQFFLPALPVFTWLALYFTCAKIPQEWKPAITVKVLPAMETILYGDNLSNVLATITTGVLDILAWLPYGIIHFSFPFVLAAIIFLFGPPTALRSFGFAFGYMNLLGVLIQMAFPAAPPWYKNLHGLEPANYSMHGSPGGLGRIDKLLGVDMYTTGFSNSSIIFGAFPSLHSGCCIMEVLFLCWLFPRFKFVWVTYASWLWWSTMYLTHHYFVDLIGGAMLSLTVFEFTKYKYLPKNKEGLFCRWSYTEIEKIDIQEIDPLSYNYIPINSNDNESRLYTRVYQESQVSPPSRAETPEAFEMSNFSRSRQSSKTQVPLSNLTNNDQVPGINEEDEEEEGDEISSSTPSVFEDEPQGSTYAASSATSVDDLDSKRN
  
Inhibitor
Name:
BDBM50333120
Synonyms:
CHEMBL1631581 | Rustmicin
Type:
Small organic molecule
Emp. Form.:
C22H34O5
Mol. Mass.:
378.5024
SMILES:
CC[C@@H]1CC(=O)[C@H](C)C(=O)[C@@](O)(CO)C\C(OC)=C\[C@@H](C)CC(=C)\C=C1/C |r,t:17,24|
Structure:
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