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Target
Carbonic anhydrase
Ligand
BDBM10876
Substrate
n/a
Meas. Tech.
ChEMBL_700659 (CHEMBL1645698)
Ki
642±n/a nM
Citation
 Bertucci, A; Innocenti, A; Scozzafava, A; Tambutté, S; Zoccola, D; Supuran, CT Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. Bioorg Med Chem Lett 21:710-4 (2011) [PubMed]  Article 
Target
Name:
Carbonic anhydrase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
35119.71
Organism:
Stylophora pistillata
Description:
ChEMBL_700659
Residue:
316
Sequence:
MYFLWLISMIAAAMCQEYGYMSEQGVPTPSNWSKVFPLCGGKFQSPINIETKKVKKKSYPDLKISFDNPCGRVTGELLNAGHSPVVNIDSSKGGAKLSGGPLDCDEYALQQFHFHFGCENSRGSEHLIDSQAFPAQLHLVFFNKKYETFQNAVDKPDGLAVLGVLITATCPGNRVLGSFAKKLTKIIEEGASANVTAVDGIKLNYLMPYNNKQGDEDEDDEDIAGDDPDAVEEEEVDAKKKIKYYTYKGSLTTPPCYESVTWIVFKDKIKISNTQLKKFRKLKAQYGGAPGLMCDNIRPVQPLHKRKVYSVLSSRE
  
Inhibitor
Name:
BDBM10876
Synonyms:
4-(hydroxymethyl)benzene-1-sulfonamide | CHEMBL6919 | JMC522226 Compound 20 | JMC523116 Compound 20 | aromatic/heteroaromatic sulfonamide 21
Type:
Small organic molecule
Emp. Form.:
C7H9NO3S
Mol. Mass.:
187.216
SMILES:
NS(=O)(=O)c1ccc(CO)cc1
Structure:
Search PDB for entries with ligand similarity: