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Target
Neuronal acetylcholine receptor subunit beta-2
Ligand
BDBM50336020
Substrate
n/a
Meas. Tech.
ChEMBL_717231 (CHEMBL1669854)
Ki
39000±n/a nM
Citation
 Lin, SW; Sun, Q; Ge, ZM; Wang, X; Ye, J; Li, RT Synthesis and structure-analgesic activity relationships of a novel series of monospirocyclopiperazinium salts (MSPZ). Bioorg Med Chem Lett 21:940-3 (2011) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit beta-2
Synonyms:
ACHB2_HUMAN | CHRNB2 | Neuronal acetylcholine receptor protein beta-2 subunit | Nicotinic acetylcholine receptor alpha3/beta2/alpha5
Type:
Protein
Mol. Mass.:
57020.50
Organism:
Homo sapiens (Human)
Description:
P17787
Residue:
502
Sequence:
MARRCGPVALLLGFGLLRLCSGVWGTDTEERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSYDGSIFWLPPAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCVLNVHHRSPTTHTMAPWVKVVFLEKLPALLFMQQPRHHCARQRLRLRRRQREREGAGALFFREAPGADSCTCFVNRASVQGLAGAFGAEPAPVAGPGRSGEPCGCGLREAVDGVRFIADHMRSEDDDQSVSEDWKYVAMVIDRLFLWIFVFVCVFGTIGMFLQPLFQNYTTTTFLHSDHSAPSSK
  
Inhibitor
Name:
BDBM50336020
Synonyms:
CHEMBL1669092 | N,N,N-trimethyl-1-(4-styrylphenoxy)propan-2-aminium iodide
Type:
Small organic molecule
Emp. Form.:
C20H26NO
Mol. Mass.:
296.426
SMILES:
CC(COc1ccc(\C=C/c2ccccc2)cc1)[N+](C)(C)C
Structure:
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