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Target
AP-2 complex subunit sigma
Ligand
BDBM50339685
Substrate
n/a
Meas. Tech.
ChEMBL_735249 (CHEMBL1694511)
Ki
5960±n/a nM
Citation
 Tu, Z; Li, S; Cui, J; Xu, J; Taylor, M; Ho, D; Luedtke, RR; Mach, RH Synthesis and pharmacological evaluation of fluorine-containing D3 dopamine receptor ligands. J Med Chem 54:1555-64 (2011) [PubMed]  Article 
Target
Name:
AP-2 complex subunit sigma
Synonyms:
AP-2 complex subunit sigma | AP2S1_RAT | Ap17 | Ap2s1 | Claps2 | Sigma-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
17016.49
Organism:
RAT
Description:
Sigma-2 0 RAT::P62744
Residue:
142
Sequence:
MIRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEFRNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEMFLAGEIRETSQTKVLKQLLMLQSLE
  
Inhibitor
Name:
BDBM50339685
Synonyms:
4-(Thiophen-3-yl)-N-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)benzamide oxalic acid salt | CHEMBL1689006
Type:
Small organic molecule
Emp. Form.:
C27H32FN3O2S
Mol. Mass.:
481.625
SMILES:
FCCOc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccsc2)CC1
Structure:
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