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Target
Cyclin-dependent kinase 19
Ligand
BDBM50341494
Substrate
n/a
Meas. Tech.
ChEMBL_741955 (CHEMBL1768607)
Kd
88±n/a nM
Citation
 Kim, O; Jeong, Y; Lee, H; Hong, SS; Hong, S Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesis. J Med Chem 54:2455-66 (2011) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 19
Synonyms:
CDC2-related protein kinase 6 | CDC2L6 | CDK11 | CDK19 | CDK19_HUMAN | Cell division cycle 2-like protein kinase 6 | Cell division protein kinase 19 | Cyclin-dependent kinase 11 | Death-preventing kinase | KIAA1028
Type:
Serine/Threonine protein kinase
Mol. Mass.:
56816.68
Organism:
Homo sapiens (Human)
Description:
Q9BWU1
Residue:
502
Sequence:
MDYDFKAKLAAERERVEDLFEYEGCKVGRGTYGHVYKARRKDGKDEKEYALKQIEGTGISMSACREIALLRELKHPNVIALQKVFLSHSDRKVWLLFDYAEHDLWHIIKFHRASKANKKPMQLPRSMVKSLLYQILDGIHYLHANWVLHRDLKPANILVMGEGPERGRVKIADMGFARLFNSPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPFHHDQLDRIFSVMGFPADKDWEDIRKMPEYPTLQKDFRRTTYANSSLIKYMEKHKVKPDSKVFLLLQKLLTMDPTKRITSEQALQDPYFQEDPLPTLDVFAGCQIPYPKREFLNEDDPEEKGDKNQQQQQNQHQQPTAPPQQAAAPPQAPPPQQNSTQTNGTAGGAGAGVGGTGAGLQHSQDSSLNQVPPNKKPRLGPSGANSGGPVMPSDYQHSSSRLNYQSSVQGSSQSQSTLGYSSSSQQSSQYHPSHQAHRY
  
Inhibitor
Name:
BDBM50341494
Synonyms:
CHEMBL1765464 | N-(5-(3-(5-Methyl-1,2,4-oxadiazol-3-yl)imidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide
Type:
Small organic molecule
Emp. Form.:
C21H16N6O3S
Mol. Mass.:
432.455
SMILES:
Cc1nc(no1)-c1cnc2ccc(cn12)-c1cncc(NS(=O)(=O)c2ccccc2)c1
Structure:
Search PDB for entries with ligand similarity: