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Target
Carbonic anhydrase 13
Ligand
BDBM35727
Substrate
n/a
Meas. Tech.
ChEMBL_753081 (CHEMBL1799009)
Ki
437±n/a nM
Citation
 Biswas, S; Aggarwal, M; Güzel, Ö; Scozzafava, A; McKenna, R; Supuran, CT Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. Bioorg Med Chem 19:3732-8 (2011) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA13 | CAH13_HUMAN | Carbonic anhydrase | Carbonic anhydrase 13 (CA XIII) | Carbonic anhydrase XIII (CA XIII)
Type:
Enzyme
Mol. Mass.:
29445.78
Organism:
Homo sapiens (Human)
Description:
Q8N1Q1
Residue:
262
Sequence:
MSRLSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKIISNSGHSFNVDFDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRFTNFDLLSLLPPSWDYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAEGEAAAFLVSNHRPPQPLKGRKVRASFH
  
Inhibitor
Name:
BDBM35727
Synonyms:
sulfonamide deriv., 5b
Type:
Small organic molecule
Emp. Form.:
C12H11FN2O3S2
Mol. Mass.:
314.356
SMILES:
NS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)c(F)c1
Structure:
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