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Target
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Ligand
BDBM50347143
Substrate
n/a
Meas. Tech.
ChEMBL_753328 (CHEMBL1799589)
IC50
70300±n/a nM
Citation
 Kellenberger, E; Kuhn, I; Schuber, F; Muller-Steffner, H Flavonoids as inhibitors of human CD38. Bioorg Med Chem Lett 21:3939-42 (2011) [PubMed]  Article 
Target
Name:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Synonyms:
CD38 | CD38_HUMAN | Lymphocyte differentiation antigen CD38
Type:
PROTEIN
Mol. Mass.:
34333.62
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1509931
Residue:
300
Sequence:
MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
  
Inhibitor
Name:
BDBM50347143
Synonyms:
FISETINIDIN
Type:
Small organic molecule
Emp. Form.:
C15H11O5
Mol. Mass.:
271.2443
SMILES:
Oc1ccc(cc1O)-c1oc2cc(=[OH+])ccc2cc1O
Structure:
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