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Target
Cyclin-dependent kinase 1
Ligand
BDBM50348241
Substrate
n/a
Meas. Tech.
ChEMBL_757435 (CHEMBL1804255)
IC50
94±n/a nM
Citation
 Lee, J; Kim, KH; Jeong, S Discovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors. Bioorg Med Chem Lett 21:4203-5 (2011) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 1
Synonyms:
CDC2 | CDC28A | CDK1 | CDK1_HUMAN | CDKN1 | Cell division control protein 2 homolog | Cell division protein kinase 1 | Cyclin-dependent kinase 1 (CDK1) | P34CDC2 | p34 protein kinase
Type:
Enzyme Subunit
Mol. Mass.:
34101.08
Organism:
Homo sapiens (Human)
Description:
P06493
Residue:
297
Sequence:
MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLDNQIKKM
  
Inhibitor
Name:
BDBM50348241
Synonyms:
CHEMBL1800452
Type:
Small organic molecule
Emp. Form.:
C17H22N4O3
Mol. Mass.:
330.3816
SMILES:
CC(C)c1cc(nc(N)n1)-c1cc(ccc1O)N1C[C@H](O)[C@@H](O)C1 |r|
Structure:
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