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Target
Enoyl-ACP reductase
Ligand
BDBM50349974
Substrate
n/a
Meas. Tech.
ChEMBL_761713 (CHEMBL1816807)
IC50
7690±n/a nM
Citation
 Bankeu, JJ; Khayala, R; Lenta, BN; Noungoué, DT; Ngouela, SA; Mustafa, SA; Asaad, K; Choudhary, MI; Prigge, ST; Hasanov, R; Nkengfack, AE; Tsamo, E; Ali, MS Isoflavone dimers and other bioactive constituents from the figs of Ficus mucuso. J Nat Prod 74:1370-8 (2011) [PubMed]  Article 
Target
Name:
Enoyl-ACP reductase
Synonyms:
Enoyl-ACP Reductase (PfENR) | Enoyl-ACP reductase
Type:
Enzyme
Mol. Mass.:
49844.02
Organism:
Plasmodium falciparum
Description:
Q9BJJ9
Residue:
432
Sequence:
MNKISQRLLFLFLHFYTTVCFIQNNTQKTFHNVLQNEQIRGKEKAFYRKEKRENIFIGNKMKHVHNMNNTHNNNHYMEKEEQDASNINKIKEENKNEDICFIAGIGDTNGYGWGIAKELSKRNVKIIFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDMLPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQSSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKSRAATAINKLNNTYENNTNQNKNRNRHDVHNIMNNSGEKEEKKISASQNYTFIDYAIEYSEKYAPLRQKLLSTDIGSVASFLLSRESRAITGQTIYVDNGLNIMFLPDDIYRNENE
  
Inhibitor
Name:
BDBM50349974
Synonyms:
CHEMBL1812485
Type:
Small organic molecule
Emp. Form.:
C40H34O10
Mol. Mass.:
674.692
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6]-c1cc(ccc1-[#8])-c1coc2c(-[#6](\[#6]=[#6](\[#6])-[#6])-c3cc(ccc3-[#8])-c3coc4cc(-[#8])cc(-[#8])c4c3=O)c(-[#8])cc(-[#8])c2c1=O
Structure:
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