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Target
Arginase
Ligand
BDBM50350311
Substrate
n/a
Meas. Tech.
ChEMBL_762136 (CHEMBL1816207)
Kd
1.1E4±n/a nM
Citation
 Ilies, M; Di Costanzo, L; Dowling, DP; Thorn, KJ; Christianson, DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem 54:5432-43 (2011) [PubMed]  Article 
Target
Name:
Arginase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
46502.96
Organism:
Plasmodium falciparum
Description:
ChEMBL_762136
Residue:
411
Sequence:
MLDTIESYIKSHKEKENLYVKKNVSIIGSPLAAGQPLGGVQLACDDLRKLGLHNVIDVLGWKYEDIGNIDNGDNEMKQEKKTNNYINNNDNNNDNNNDNNNDNNNNCYIPNGVIKEKKHDLSNNKMNGYVNHNFYGNYEENNVISTNDKYKNNCYYDNIRNIKEIGIFSKNLFDTMSNELRKKNFVLNIGGDHGVAFSSILSSLQMYQNLRVIWIDAHGDINIPETSPSGNYHGMTLAHTLGLFKKKVPYFEWSEKLTYLKPENTAIIGIRDIDAYEKIILKKCNINYYTIFDIEKNGIYNTICTALEKIDPNSNCPIHISLDIDSVDNVFAPGTGTVAKGGLNYREINLLMKILAETKRVVSMDLVEYNPSLDEVDKKVHGDSLPILDNATKTGKLCLELIARVLGYDIV
  
Inhibitor
Name:
BDBM50350311
Synonyms:
CHEMBL1812661
Type:
Small organic molecule
Emp. Form.:
C6H14BNO4
Mol. Mass.:
174.991
SMILES:
[NH3+][C@@H](CCCCB(O)O)C([O-])=O |r|
Structure:
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