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Target
5-hydroxytryptamine receptor 1D
Ligand
BDBM50353903
Substrate
n/a
Meas. Tech.
ChEMBL_769754 (CHEMBL1831560)
IC50
>10000±n/a nM
Citation
 Lebar, MD; Hahn, KN; Mutka, T; Maignan, P; McClintock, JB; Amsler, CD; van Olphen, A; Kyle, DE; Baker, BJ CNS and antimalarial activity of synthetic meridianin and psammopemmin analogs. Bioorg Med Chem 19:5756-62 (2011) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1D
Synonyms:
5-HT-1D | 5-HT-1D-alpha | 5-HT1D | 5-hydroxytryptamine receptor 1D (5-HT1D) | 5HT1D_HUMAN | HTR1D | HTR1DA | HTRL | Serotonin (5-HT) receptor | Serotonin Receptor 1D
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
41920.63
Organism:
Homo sapiens (Human)
Description:
Receptor binding assays were performed using human clone stably expressed in CHO cells.
Residue:
377
Sequence:
MSPLNQSAEGLPQEASNRSLNATETSEAWDPRTLQALKISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAYTITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATMIAIVWAISICISIPPLFWRQAKAQEEMSDCLVNTSQISYTIYSTCGAFYIPSVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAGSPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS
  
Inhibitor
Name:
BDBM50353903
Synonyms:
CHEMBL1829961
Type:
Small organic molecule
Emp. Form.:
C12H9ClN4O
Mol. Mass.:
260.679
SMILES:
Nc1nc(Cl)ncc1-c1c[nH]c2cccc(O)c12
Structure:
Search PDB for entries with ligand similarity: