Reaction Details Report a problem with these data
Target
Sialidase
Ligand
BDBM50355211
Substrate
n/a
Meas. Tech.
ChEMBL_772883 (CHEMBL1838286)
Ki
1200±n/a nM
Citation
 Woo, HS; Kim, DW; Curtis-Long, MJ; Lee, BW; Lee, JH; Kim, JY; Kang, JE; Park, KH Potent inhibition of bacterial neuraminidase activity by pterocarpans isolated from the roots of Lespedeza bicolor. Bioorg Med Chem Lett 21:6100-3 (2011) [PubMed]  Article 
Target
Name:
Sialidase
Synonyms:
NANH_CLOPF | nanH
Type:
PROTEIN
Mol. Mass.:
42808.79
Organism:
Clostridium perfringens
Description:
ChEMBL_991336
Residue:
382
Sequence:
MCNKNNTFEKNLDISHKPEPLILFNKDNNIWNSKYFRIPNIQLLNDGTILTFSDIRYNGPDDHAYIDIASARSTDFGKTWSYNIAMKNNRIDSTYSRVMDSTTVITNTGRIILIAGSWNTNGNWAMTTSTRRSDWSVQMIYSDDNGLTWSNKIDLTKDSSKVKNQPSNTIGWLGGVGSGIVMDDGTIVMPAQISLRENNENNYYSLIIYSKDNGETWTMGNKVPNSNTSENMVIELDGALIMSTRYDYSGYRAAYISHDLGTTWEIYEPLNGKILTGKGSGCQGSFIKATTSNGHRIGLISAPKNTKGEYIRDNIAVYMIDFDDLSKGVQEICIPYPEDGNKLGGGYSCLSFKNNHLGIVYEANGNIEYQDLTPYYSLINKQ
  
Inhibitor
Name:
BDBM50355211
Synonyms:
CHEMBL1835716
Type:
Small organic molecule
Emp. Form.:
C31H38O4
Mol. Mass.:
474.631
SMILES:
[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-c1cc2-[#6@@H]-3-[#8]-c4c(cc(-[#6])c(-[#8])c4-[#6]\[#6]=[#6](\[#6])-[#6])-[#6@@H]-3-[#6]-[#8]-c2cc1-[#8] |r|
Structure:
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