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Target
Cyclin-dependent kinase 17
Ligand
BDBM25919
Substrate
n/a
Meas. Tech.
ChEMBL_774256 (CHEMBL1908473)
Kd
>10000±n/a nM
Citation
 Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol 29:1046-51 (2011) [PubMed]  Article 
Target
Name:
Cyclin-dependent kinase 17
Synonyms:
CDK17 | CDK17_HUMAN | PCTAIRE2 | PCTK2 | Serine/threonine-protein kinase PCTAIRE-2
Type:
PROTEIN
Mol. Mass.:
59600.69
Organism:
Homo sapiens (Human)
Description:
ChEMBL_586854
Residue:
523
Sequence:
MKKFKRRLSLTLRGSQTIDESLSELAEQMTIEENSSKDNEPIVKNGRPPTSHSMHSFLHQYTGSFKKPPLRRPHSVIGGSLGSFMAMPRNGSRLDIVHENLKMGSDGESDQASGTSSDEVQSPTGVCLRNRIHRRISMEDLNKRLSLPADIRIPDGYLEKLQINSPPFDQPMSRRSRRASLSEIGFGKMETYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGPRIHALPESVSIFSLKEIQLQKDPGFRNSSYPETGHGKNRRQSMLF
  
Inhibitor
Name:
BDBM25919
Synonyms:
BMS-345541 | BMS345541 | CHEMBL471496 | N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13),3,5,7,9,11-hexaen-7-amine
Type:
Small organic molecule
Emp. Form.:
C14H17N5
Mol. Mass.:
255.3183
SMILES:
Cc1cnc2c(NCCN)nc3ccc(C)cc3n12
Structure:
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