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Target
Cannabinoid receptor 2
Ligand
BDBM50356013
Substrate
n/a
Meas. Tech.
ChEMBL_775351 (CHEMBL1912836)
Kd
>10000±n/a nM
Citation
 Yang, Y; Miller, KJ; Zhu, Y; Hong, Y; Tian, Y; Murugesan, N; Gu, Z; O'Tanyi, E; Keim, WJ; Rohrbach, KW; Johnghar, S; Behnia, K; Pelleymounter, MA; Carlson, KE; Ewing, WR Characterization of a novel and selective CB1 antagonist as a radioligand for receptor occupancy studies. Bioorg Med Chem Lett 21:6856-60 (2011) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50356013
Synonyms:
CHEMBL1911374 | CHEMBL1911375
Type:
Small organic molecule
Emp. Form.:
C23H14ClF3N6O
Mol. Mass.:
482.845
SMILES:
FC(F)(F)c1ccc(Cn2nc3c(-c4ccncc4)c(cnn3c2=O)-c2ccc(Cl)cc2)cn1
Structure:
Search PDB for entries with ligand similarity: