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Target
D(1A) dopamine receptor
Ligand
BDBM50358841
Substrate
n/a
Meas. Tech.
ChEMBL_790592 (CHEMBL1926045)
Ki
35000±n/a nM
Citation
 Kügler, F; Sihver, W; Ermert, J; Hübner, H; Gmeiner, P; Prante, O; Coenen, HH Evaluation of 18F-labeled benzodioxine piperazine-based dopamine D4 receptor ligands: lipophilicity as a determinate of nonspecific binding. J Med Chem 54:8343-52 (2011) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DRD1 | DRD1_PIG | Dopamine D1 receptor
Type:
PROTEIN
Mol. Mass.:
49269.92
Organism:
Sus scrofa
Description:
ChEMBL_1460140
Residue:
446
Sequence:
MRTLNTSTMDGTGLVVERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNVTSLGKTTHNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTAGNGNPAECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTSTNAIETVSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIASPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50358841
Synonyms:
CHEMBL1923416
Type:
Small organic molecule
Emp. Form.:
C18H20FN3O2
Mol. Mass.:
329.3687
SMILES:
Fc1ccc(CN2CCN(CC2)c2ccc3OCCOc3c2)cn1
Structure:
Search PDB for entries with ligand similarity: