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Target
Kappa-type opioid receptor
Ligand
BDBM50361992
Substrate
n/a
Meas. Tech.
ChEMBL_799948 (CHEMBL1941654)
Ki
419±n/a nM
Citation
 Maisonial, A; Grosse Maestrup, E; Wiese, C; Hiller, A; Schepmann, D; Fischer, S; Deuther-Conrad, W; Steinbach, J; Brust, P; Wünsch, B Synthesis, radiofluorination and pharmacological evaluation of a fluoromethyl spirocyclic PET tracer for centrals1 receptors and comparison with fluoroalkyl homologs. Bioorg Med Chem 20:257-69 (2011) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50361992
Synonyms:
CHEMBL1939699
Type:
Small organic molecule
Emp. Form.:
C23H28FNO
Mol. Mass.:
353.4729
SMILES:
FCCCCC1OC2(CCN(Cc3ccccc3)CC2)c2ccccc12
Structure:
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