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Target
Secreted chorismate mutase
Ligand
BDBM50363851
Substrate
n/a
Meas. Tech.
ChEMBL_802224 (CHEMBL1949382)
IC50
19740±n/a nM
Citation
 Kumar, KS; Rambabu, D; Sandra, S; Kapavarapu, R; Krishna, GR; Basaveswara Rao, MV; Chatti, K; Reddy, CM; Misra, P; Pal, M AlCl3 induced (hetero)arylation of 2,3-dichloroquinoxaline: a one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents. Bioorg Med Chem 20:1711-22 (2012) [PubMed]  Article 
Target
Name:
Secreted chorismate mutase
Synonyms:
Chorismate mutase (CM) | Chorismate mutase (MTB CM) | Chorismate mutase-related protein | SCMU_MYCTU
Type:
Protein
Mol. Mass.:
21942.03
Organism:
Mycobacterium tuberculosis H37Rv
Description:
n/a
Residue:
199
Sequence:
MLTRPREIYLATAVSIGILLSLIAPLGPPLARADGTSQLAELVDAAAERLEVADPVAAFKWRAQLPIEDSGRVEQQLAKLGEDARSQHIDPDYVTRVFDDQIRATEAIEYSRFSDWKLNPASAPPEPPDLSASRSAIDSLNNRMLSQIWSHWSLLSAPSCAAQLDRAKRDIVRSRHLDSLYQRALTTATQSYCQALPPA
  
Inhibitor
Name:
BDBM50363851
Synonyms:
CHEMBL1945938
Type:
Small organic molecule
Emp. Form.:
C16H8ClF2N3
Mol. Mass.:
315.705
SMILES:
Fc1cc2[nH]cc(-c3nc4ccccc4nc3Cl)c2cc1F
Structure:
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