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Target
P2Y purinoceptor 6
Ligand
BDBM50118239
Substrate
n/a
Meas. Tech.
ChEMBL_805344 (CHEMBL1955237)
EC50
200±n/a nM
Citation
 Yelovitch, S; Camden, J; Weisman, GA; Fischer, B Boranophosphate isoster controls P2Y-receptor subtype selectivity and metabolic stability of dinucleoside polyphosphate analogues. J Med Chem 55:437-48 (2012) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 6
Synonyms:
P2RY6_RAT | P2ry6 | Pyrimidinergic receptor P2Y6
Type:
PROTEIN
Mol. Mass.:
36704.21
Organism:
Rattus norvegicus
Description:
ChEMBL_805344
Residue:
328
Sequence:
MERDNGTIQAPGLPPTTCVYREDFKRLLLPPVYSVVLVVGLPLNVCVIAQICASRRTLTRSAVYTLNLALADLLYACSLPLLIYNYARGDHWPFGDLACRLVRFLFYANLHGSILFLTCISFQRYLGICHPLAPWHKRGGRRAAWVVCGVVWLVVTAQCLPTAVFAATGIQRNRTVCYDLSPPILSTRYLPYGMALTVIGFLLPFTALLACYCRMARRLCRQDGPAGPVAQERRSKAARMAVVVAAVFVISFLPFHITKTAYLAVRSTPGVSCPVLETFAAAYKGTRPFASANSVLDPILFYFTQQKFRRQPHDLLQKLTAKWQRQRV
  
Inhibitor
Name:
BDBM50118239
Synonyms:
CHEMBL130266 | UDP | Uridine diphosphate | uridine 5'-(trihydrogen diphosphate)
Type:
Small organic molecule
Emp. Form.:
C9H14N2O12P2
Mol. Mass.:
404.1612
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O |r|
Structure:
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