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Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM50156547
Substrate
n/a
Meas. Tech.
ChEMBL_808315 (CHEMBL1961332)
Ki
86±n/a nM
Citation
 Kambe, T; Maruyama, T; Nakai, Y; Yoshida, H; Oida, H; Maruyama, T; Abe, N; Nishiura, A; Nakai, H; Toda, M Discovery of novel prostaglandin analogs as potent and selective EP2/EP4 dual agonists. Bioorg Med Chem 20:2235-51 (2012) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
PE2R3_MOUSE | PGE receptor, EP3 isoform alpha | Prostaglandin E2 receptor EP3 isoform alpha | Prostaglandin E3 | Prostanoid EP3 receptor | Ptger3 | Ptgerep3
Type:
G-protein coupled receptor
Mol. Mass.:
40092.50
Organism:
Mus musculus (Mouse)
Description:
n/a
Residue:
365
Sequence:
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
  
Inhibitor
Name:
BDBM50156547
Synonyms:
4-(2-((R)-2-((S)-3-hydroxyoct-1-enyl)-5-oxopyrrolidin-1-yl)ethyl)benzoate | 4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid | CHEMBL222715
Type:
Small organic molecule
Emp. Form.:
C21H29NO4
Mol. Mass.:
359.4593
SMILES:
CCCCC[C@H](O)\C=C\[C@H]1CCC(=O)N1CCc1ccc(cc1)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: