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Target
Protein tyrosine phosphatase receptor type C-associated protein
Ligand
BDBM50284797
Substrate
n/a
Meas. Tech.
ChEBML_210870
IC50
107000±n/a nM
Citation
 Miski, M; Xing, Shen; Cooper, R; Gillum, AM; Fisher, DK; Miller, RW; Higgins, TJ Aporphine alkaloids, CD45 protein tyrosine phosphatase inhibitors, from Rollinia ulei Bioorg Med Chem Lett 5:1519-1522 (1995)    Article 
Target
Name:
Protein tyrosine phosphatase receptor type C-associated protein
Synonyms:
CD45-AP | CD45-associated protein | LPAP | Lymphocyte phosphatase-associated phosphoprotein | PTCA_HUMAN | PTPRC-associated protein | PTPRCAP
Type:
PROTEIN
Mol. Mass.:
21182.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_210870
Residue:
206
Sequence:
MALPCTLGLGMLLALPGALGSGGSAEDSVGSSSVTVVLLLLLLLLLATGLALAWRRLSRDSGGYYHPARLGAALWGRTRRLLWASPPGRWLQARAELGSTDNDLERQEDEQDTDYDHVADGGLQADPGEGEQQCGEASSPEQVPVRAEEARDSDTEGDLVLGSPGPASAGGSAEALLSDLHAFAGSAAWDDSARAAGGQGLHVTAL
  
Inhibitor
Name:
BDBM50284797
Synonyms:
7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline | CHEMBL36654 | GNF-Pf-4466 | cid_235224
Type:
Small organic molecule
Emp. Form.:
C18H17NO2
Mol. Mass.:
279.3331
SMILES:
CN1CCc2cc3OCOc3c3-c4ccccc4CC1c23
Structure:
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