Reaction Details Report a problem with these data
Target
Glutamyl aminopeptidase
Ligand
BDBM50078122
Substrate
n/a
Meas. Tech.
ChEBML_32826
Ki
0.000±n/a nM
Comments
0.0000400 01/04/22
Citation
 Chen, H; Roques, BP; Fournié-Zaluski, MC Design of the first highly potent and selective aminopeptidase N (EC 3.4.11.2) inhibitor. Bioorg Med Chem Lett 9:1511-6 (1999) [PubMed]  Article 
Target
Name:
Glutamyl aminopeptidase
Synonyms:
APA | CD_antigen=CD249 | EAP | Glutamyl aminopeptidase | AMPE_PIG | ENPEP | Aminopeptidase A
Type:
PROTEIN
Mol. Mass.:
108259.08
Organism:
Pig
Description:
ChEMBL_32826
Residue:
942
Sequence:
MSTDSKRYCIKTKHVAIICAAVVAVGLIVGLSVGLTRSCDSKDGGQGTTQSPSHLPPTSSPPQDQGVCPASEDESGNWRDFRLPDFINPVHYDLQVKPLLEQDTYTGTVNISINVTSPTQHLWLHLRETRITQLPVLWRPSGEQVQVRRCFEYKKQEYVVVEAEEELAPNSGEGLYHLTMEFAGWLNGSLVGFYRTTYVEKGQIKSIAATDHEPTDARKSFPCFDEPNKKATYTISIIHPKEYKALSNMPVEKEESVDDIWTQTTFQKSVPMSTYLVCFAVHQFDSVTRTSRSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEDYFAMEYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPNESASSNQQRVAAVVAHELVHQWFGNIVTMEWWEDLWLNEGFASFFEFLGVDHAEKEWQMRDQILLEDVLPVQEDDSLISSHPIVVTVSTPAEITSVFDGISYSKGASILRMLEDWITPEKFQKGCQEYLKKFEFKNAKTSDFWEALEEASNLPVKEVMDTWTNQMGYPVLNVEDMRIISQKRFLLDPNANSSEPHSVFGYTWNIPVRWTNDNESTITIYNRSETGGITLNSSNPNGNAFLKINPDHIGFYRVNYEVSTWEWIATNLSLNHKDFSTADRASLIDDAFALARAQLLNYKEALNLTKYLKMEDEYLPWQRVISAVTYIISMFEDDKELYPMIEKYFRDQVKPIADSLGWNDNGDHLTKLLRASVLGFACKMGDSNALNNASHLFEQWLTGTVSLPVNLRLLVYRYGMQNSGNETSWNYTLKQYQETSLAQEKEKLLYGLASVKNVALLSRYLDLLKDPNVIKSQDVFTVIRYISYNSYGKTMAWNWIQLNWEYLVNRYTLNDRNLGRIVTIAEPFNTELQLWQMESFFKRYPEAGAGEKPREQVLETVKNNIEWLKQNRDTIRDWFFN
  
Inhibitor
Name:
BDBM50078122
Synonyms:
(R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-ethylcarbamoyl)-3-phenyl-propyl]-hydroxy-phosphinoyl}-2-phenyl-ethyl-ammonium
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: