Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM50086644
Substrate
n/a
Meas. Tech.
ChEBML_214525
Ki
2600000±n/a nM
Citation
 Ibrahimi, OA; Wu, L; Zhao, K; Zhang, ZY Synthesis and characterization of a novel class of protein tyrosine phosphatase inhibitors. Bioorg Med Chem Lett 10:457-60 (2000) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM50086644
Synonyms:
[4-(carboxymethyl)phenoxy]methylphosphonate
Type:
Small organic molecule
Emp. Form.:
C9H9O6P
Mol. Mass.:
244.139
SMILES:
OC(=O)Cc1ccc(OCP([O-])([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: