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Target
D(3) dopamine receptor
Ligand
BDBM50112802
Substrate
n/a
Meas. Tech.
ChEBML_62274
Ki
27±n/a nM
Citation
 Cha, MY; Choi, BC; Kang, KH; Pae, AN; Choi, KI; Cho, YS; Koh, HY; Lee, HY; Jung, D; Kong, JY Design and synthesis of a piperazinylalkylisoxazole library for subtype selective dopamine receptor ligands. Bioorg Med Chem Lett 12:1327-30 (2002) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50112802
Synonyms:
1-Phenyl-4-[4-(3-styryl-isoxazol-5-yl)-butyl]-piperazine; hydrochloride | CHEMBL543277
Type:
Small organic molecule
Emp. Form.:
C25H29N3O
Mol. Mass.:
387.5173
SMILES:
C(CCc1cc(\C=C\c2ccccc2)no1)CN1CCN(CC1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: